Developing and implementation of a new generation of nanosafety assessment tools
NANOGENTOOLS project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement n° 691095
Project durationt: 01 January 2016 - 31 December 2019 (48 months)
Total cost: EUR 706.500
EU contribution: EUR 706.500
Number of partners: 8 (incl. coordinator)
BNN members participating: SITEX 45 SRL, Novomechanics
Coordinator: Universidad de Burgos (Spain)
Project keywords: Nanochemistry, Environment chemistry, Nano-materials (production and properties)
Project summary & objectives:
The H2020 Marie-Sklodowska-Curie-Action NANOGENTOOLS aims at developing new methodologies for the identification and control of hazards associated with nanomaterials, ensuring consumer and society safety. It pursues the main objective of generating a common solid knowledge basis arising from the fruitful cross-sectorial synergy between forefront research centers in nanosafety and industry, in a cross-fertilization multidisciplinary approach that will provide new tests and methodologies (or improve existing ones) to assess the long term risks of nanomaterials (NMs) in a rapid and cost effective manner suitable for regulatory inclusion.
NANOGENTOOLS combines genomics (toxicogenomics), proteomics and multidisciplinary science (biophysics, molecular modelling, chemistry, bioinformatics, chemoinformatics) to develop fast in vitro high throughput (HTS) assays, with molecular based computational models for better understanding of the molecular fundamentals of nanotoxicity, and it will initiate the development of online nanosafety assays for use by SMEs during product development.
The specific objectives of the project are:
- To provide solutions for faster and more reliable assessment of NM toxicity and propose a battery of HTS and -omics tools suitable for predicting the toxicological properties of NMs.
- To develop new bioinformatics methodologies capable of analyzing -omics data and create an open database for the scientific community in collaboration with the EU Nanosafety Cluster.
- To conduct research and training on biophysical techniques and mathematical models for accurate and fast nanotoxicity prediction linked to safety-by-design concepts.
- To understand, build and improve the safe by design concept, with demonstration using carbon-based NMs and nanosensors and demonstrate translation across applications and NMs.
- To place our new knowledge in the context of present regulations and EU roadmaps.
Role of BNN:
BNN is partner of the NANOGENTOOLS project. BNN is responsible for the organization of workshops focussing on interlinking the methodologies addressed by NANOGENTOOLS, and their importance as new vehicles for nanosafety assessment. Furthermore, webinars will be carried out and training sessions will be organized throughout the project lifespan, involving participation of all partners in order to discuss and understand the regulatory impact of nanosafety recommendations arising from new methodologies. Moreover, BNN supports communication and dissemination activities as well as exploitation of the project’s results.
- keywords: workshop, nanosafety, assessment, training session, communication, dissemination
For more details please visit the project website www3.ubu.es/nanogentools and the Cordis-project entry https://cordis.europa.eu/.